*Result*: Dynamics of Triatoma infestans populations in the Paraguayan Chaco : population genetic analysis of household reinfestation following vector control

Title:
Dynamics of Triatoma infestans populations in the Paraguayan Chaco : population genetic analysis of household reinfestation following vector control
Authors:
Rojas de Arias, Gladys Antonieta, Messenger, Louisa Alexandra, Rolón, Miriam Soledad, Vega Gómez, María Celeste, Acosta Garcete, Nidia Genoveva, Villalba, Cesia, Marcet, Paula L.
Publisher Information:
Public Library of Science
Publication Year:
2022
Subject Terms:
Calidad de la vivienda, Control de insectos/métodos, Enfermedad de Chagas, Flujo génico, Genotipo, Insecticidas, Insectos vectores/genética, Prevalencia, Triatoma/genética, Housing quality, Insect control/methods, Chagas Disease, Gene flow, Genotype, Insecticides, Insect vectors/genetics, Prevalence, Triatoma/genetics
Document Type:
*Academic Journal* article in journal/newspaper
Language:
English
Relation:
Rojas de Arias, A., Messenger, L. A., Rolon, M., Vega, M. C., Acosta, N., Villalba, C., & Marcet, P. L. (2022). Dynamics of Triatoma infestans populations in the Paraguayan Chaco: Population genetic analysis of household reinfestation following vector control. PLOS ONE, 17(2), Artículo e0263465. https://doi.org/10.1371/journal.pone.0263465; https://doi.org/10.1371/journal.pone.0263465; https://hdl.handle.net/20.500.14066/4427
DOI:
10.1371/journal.pone.0263465
Availability:
https://hdl.handle.net/20.500.14066/4427
https://doi.org/10.1371/journal.pone.0263465
Rights:
CC0 1.0 Universal ; http://creativecommons.org/publicdomain/zero/1.0/ ; open access ; This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
Accession Number:
edsbas.9F12BE64
Database:
BASE

*Further Information*

*Correspondence: Gladys Antonieta Rojas de Arias, rojasdearias@gmail.com ; Background. Although domestic infestations by Triatoma infestans have been successfully controlled across Latin America, in areas of the Gran Chaco region, recurrent post-spraying house colonization continues to be a significant challenge, jeopardizing Chagas disease vector control and maintaining active Trypanosoma cruzi transmission. Methodology/Principal findings. To investigate the dynamics of triatomine reinfestation in a rural area of the Paraguayan Chaco, genetic characterization (based on 10 microsatellite loci and cytochrome B sequence polymorphisms) was performed on baseline and reinfestant T. infestans (n = 138) from four indigenous communities and adjacent sylvatic sites. House quality and basic economic activities were assessed across the four communities. Significant genetic differentiation was detected among all baseline triatomine populations. Faster reinfestation was observed in the communities with higher infestation rates pre-spraying. Baseline and reinfestant populations from the same communities were not genetically different, but two potentially distinct processes of reinfestation were evident. In Campo Largo, the reinfestant population was likely founded by domestic survivor foci, with reduced genetic diversity relative to the baseline population. However, in 12 de Junio, reinfestant bugs were likely derived from different sources, including survivors from the pre-spraying population and sympatric sylvatic bugs, indicative of gene-flow between these habitats, likely driven by high human mobility and economic activities in adjacent sylvatic areas. Conclusions/Significance. Our results demonstrate that sylvatic T. infestans threatens vector control strategies, either as a reinfestation source or by providing a temporary refuge during insecticide spraying. Passive anthropogenic importation of T. infestans and active human interactions with neighboring forested areas also played a role in recolonization. Optimization of ...*