Treffer: Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Javier Benitez, Marie Stenmark-Askmalm, Susan L. Neuhausen, Pascal Guénel, Jane Carpenter, Christine B. Ambrosone, Dominique Stoppa-Lyonnet, Nadine Tung, Gad Rennert, Stephen J. Chanock, Andrew K. Godwin, Regina M. Santella, Brita Arver, Karoline Kuchenbaecker, Kamila Czene, Vessela N. Kristensen, Natalia Bogdanova, Nazneen Rahman, Jianjun Liu, Federico Canzian, Hoda Anton-Culver, Maya Ghoussaini, Mark E. Robson, Sue K. Park, Manjeet K. Bolla, Roger L. Milne, Veli-Matti Kosma, Siranoush Manoukian, Angela Cox, Daniel F. Schmidt, Kay-Tee Khaw, Rosario Tumino, Melissa C. Southey, Ramunas Janavicius, Irene Konstantopoulou, Carl Blomqvist, John L. Hopper, Sue Healey, Christine Rappaport, Marco Montagna, SA Gayther, Heather Eliassen, Carolien H.M. van Deurzen, Jacques Simard, Emiel J. Rutgers, Jonine Figueroa, Maria A. Caligo, Volker Arndt, Sylvie Mazoyer, Diana Eccles, M.J. Hooning, Antoinette Hollestelle, Mary B. Daly, Robert Winqvist, Antonis C. Antoniou, Patricia A. Ganz, Orland Diez, Priyanka Sharma, Ana Osorio, Daniel Barrowdale, Loic Le Marchand, Drakoulis Yannoukakos, Elinor J. Sawyer, Conxi Lázaro, Soo-Hwang Teo, Penny Soucy, Paolo Radice, John W. M. Martens, Steve Ellis, David E. Goldgar, Anna Jakubowska, Maria Kabisch, Raymonda Varon-Mateeva, Diether Lambrechts, Paul D.P. Pharoah, Leigha Senter, Anna González-Neira, Cecilia M. Dorfling, Brian E. Henderson, Rulla M. Tamimi, Sara Margolin, Susan M. Gapstur, Ian Tomlinson, Thérèse Truong, Robert A.E.M. Tollenaar, Amanda E. Toland, Anna Marie Mulligan, Irene L. Andrulis, Isabelle Romieu, Monica Barile, Florentia Fostira, Johanna Rantala, Enes Makalic, Eitan Friedman, Zhaoming Wang, Mark H. Greene, Noralane M. Lindor, Julie M. Cunningham, Riccardo Dolcetti, Steven N. Hart, Mary Beth Terry, Jenny Chang-Claude, Austin Miller, Georgia Chenevix-Trench, Asta Försti, Kathleen E. Malone, Paolo Peterlongo, Lothar Haeberle, Celine M. Vachon, Elizabeth J. van Rensburg, Michael Jones, Laima Tihomirova, Penelope Miron, Eunjung Lee, María José Sánchez, Hatef Darabi, Frans B. L. Hogervorst, Matthias W. Beckmann, Edith Olah, Annika Lindblom, Phuong L. Mai, Emily Hallberg, Alison M. Dunning, Kathleen Claes, Esther M. John, Sofia Khan, David J. Hunter, Kristiina Aittomäki, Katherine L. Nathanson, Lars Beckmann, Stephanie V. Blank, Wei Zheng, Olufunmilayo I. Olopade, Heli Nevanlinna, Miguel de la Hoya, Olga M. Sinilnikova, Bruce Poppe, Catherine M. Phelan, S. Lindstrom, Stig E. Bojesen, Curtis Olswold, Fredrick R. Schumacher, Janet E. Olson, Tuomas Heikkinen, Judy Garber, Fergus J. Couch, Tara M. Friebel, Isabel dos-Santos-Silva, Douglas F. Easton, Song Yao, Dieter Flesch-Janys, Hans Ehrencrona, Simon S. Cross, Rodney J. Scott, Kenneth Offit, Petra H.M. Peeters, Clare Turnbull, Taru A. Muranen, William J. Tapper, Trinidad Caldés, Jenny Lester, Robert L. Nussbaum, Paul A. James, Marike Gabrielson, Susan M. Domchek, Mads Thomassen, Marilie D. Gammon, Susan L. Slager, Graham G. Giles, Silje Nord, Hans Wildiers, Hiltrud Brauch, Gustavo Mendoza-Fandiño, Christopher A. Haiman, Martine Dumont, Mark S. Goldberg, Bernardo Bonanni, Jirong Long, Kyriaki Michailidou, Ute Hamann, Wendy K. Chung, Marc J. Gunter, Mia M. Gaudet, Keith Humphreys, Per Hall, Yuan C. Ding, Simona Agata, Julia A. Knight, Robert Pilarski, Claudine Isaacs, Alvaro A.N. Monteiro, Montserrat Garcia-Closas, Rosa B. Barkardottir, Beth Y. Karlan, Uffe Birk Jensen, Arif B. Ekici, Evgeny N. Imyanitov, Alex Teulé, Anne-Marie Gerdes, Frederik Marme, Debra Frost, Anthony J. Swerdlow, Yon Ko, Xiaohong R. Yang, Jan Lubinski, Peter A. Fasching, Lesley McGuffog, Jacek Gronwald, Katri Pylkäs, Banu Arun, Josef Herzog, Gord Glendon, Doris Steinemann, Tomasz Huzarski, Peter Kraft, Anja Rudolph, Arto Mannermaa, Habibul Ahsan, Christian F. Singer, Rita K. Schmutzler, Julian Peto, Giski Ursin, Shan Wang-Gohrke, Andrea L. Richardson, Jeffrey N. Weitzel, Børge G. Nordestgaard, Marjanka K. Schmidt, Alice S. Whittemore, Hermann Brenner, Barbara Burwinkel, D Thompson, Csilla I. Szabo, M. Pilar Zamora, Janna Lilyquist, Muhammad G. Kibriya, Yael Laitman, Helen Tsimiklis, W. D. Foulkes, Thomas Hansen, Francesca Damiola, Robert N. Hoover, Ava Kwong, Alfons Meindl, Siddhartha Kar, Manuel R. Teixeira, Elisabete Weiderpass, Bernard Peissel, Saundra S. Buys, Peter Devilee

Unión Europea. Comisión Europea. 7 Programa Marco, Cancer Research UK (Reino Unido), National Institutes of Health (Estados Unidos), Canadian Institutes of Health Research, Florida Breast Cancer Foundation (Estados Unidos), Dunning, Alison [0000-0001-6651-7166], Ghoussaini, Maya [0000-0002-2415-2143], Khaw, Kay-Tee [0000-0002-8802-2903], Thompson, Deborah [0000-0003-1465-5799], Pharoah, Paul [0000-0001-8494-732X], Easton, Douglas [0000-0003-2444-3247], Antoniou, Antonis [0000-0001-9223-3116], Apollo - University of Cambridge Repository, Medical Oncology, Obstetrics & Gynecology, Pathology, Cell biology, Medicum, Kristiina Aittomäki / Principal Investigator, Department of Medical and Clinical Genetics, Clinicum, Department of Oncology, Department of Obstetrics and Gynecology, HUS Gynecology and Obstetrics, [ 1 ] Mayo Clin, Dept Lab Med & Pathol, Rochester, MN 55905 USA [ 2 ] Mayo Clin, Dept Hlth Sci Res, Rochester, MN 55905 USA [ 3 ] Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England [ 4 ] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Canc Epidemiol Program, Tampa, FL 33612 USA [ 5 ] Radiumhosp, Oslo Univ Hosp, Inst Canc Res, Dept Genet, N-0310 Oslo, Norway [ 6 ] IRCCS, IOV, Immunol & Mol Oncol Unit, I-20133 Padua, Italy [ 7 ] Univ Chicago, Dept Hlth Studies, Chicago, IL 60637 USA [ 8 ] Univ Chicago, Ctr Comprehens Canc, Chicago, IL 60637 USA [ 9 ] Univ Chicago, Dept Med & Human Genet, Chicago, IL 60637 USA [ 10 ] Univ Helsinki, Cent Hosp, Dept Clin Genet, Helsinki 00029, Finland [ 11 ] Roswell Pk Canc Inst, Dept Canc Prevent & Control, Buffalo, NY 14263 USA [ 12 ] Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON M5G 1X5, Canada [ 13 ] Univ Toronto, Dept Mol Genet, Toronto, ON M5B 1W8, Canada [ 14 ] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON M5B 1W8, Canada [ 15 ] Univ Calif Irvine, Dept Epidemiol, Irvine, CA 92697 USA [ 16 ] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany [ 17 ] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA [ 18 ] Karolinska Univ Hosp, Dept Oncol, SE-17176 Stockholm, Sweden [ 19 ] Ist Europeo Oncol, Div Canc Prevent & Genet, I-20141 Milan, Italy [ 20 ] Landspitali Univ Hosp, Dept Pathol, IS-101 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital [ 21 ] Univ Iceland, Sch Med, IS-101 Reykjavik, Iceland [ 22 ] Inst Qual & Efficiency Hlth Care IQWiG, D-50670 Cologne, Germany [ 23 ] Univ Erlangen Nurnberg, Comprehens Canc Ctr Erlangen EMN, Univ Breast Ctr Franconia, Dept Gynecol & Obstet,Univ Hosp Erlangen, D-91054 Erlangen, Germany [ 24 ] Spanish Natl Canc Ctr CNIO, Human Genet Grp, Human Canc Genet Program, Madrid 28029, Spain [ 25 ] Spanish Natl Canc Ctr CNIO, Human Canc Genet Program, Genotyping Unit CeGen, Madrid 28029, Spain [ 26 ] Biomed Network Rare Dis CIBERER, Madrid 28029, Spain [ 27 ] NYU, Sch Med, NYU Womens Canc Program, New York, NY 10016 USA [ 28 ] Univ 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Couch, F J, Kuchenbaecker, K B, Michailidou, K, Mendoza-Fandino, G A, Nord, S, Lilyquist, J, Olswold, C, Hallberg, E, Agata, S, Ahsan, H, Aittomäki, K, Ambrosone, C, Andrulis, I L, Anton-Culver, H, Arndt, V, Arun, B K, Arver, B, Barile, M, Barkardottir, R B, Barrowdale, D, Beckmann, L, Beckmann, M W, Benítez, J, Blank, S V, Blomqvist, C, Bogdanova, N V, Bojesen, S E, Bolla, M K, Bonanni, B, Brauch, H, Brenner, H, Burwinkel, B, Buys, S, Caldes, T, Caligo, M A, Canzian, F, Carpenter, J, Chang-Claude, J, Chanock, S J, Chung, W K, Claes, K B M, Cox, A, Cross, S S, Cunningham, J M, Czene, K, Daly, M B, Damiola, F, Darabi, H, de la Hoya, M, Devilee, P, Díez, O, Ding, Y C, Dolcetti, R, Domchek, S M, Dorfling, C M, Dos Santos Silva, I, Dumont, M, Dunning, A M, Eccles, D M, Ehrencrona, H, Ekici, A B, Eliassen, H, Ellis, S, Fasching, P A, Figueroa, J, Flesch-Janys, D, Försti, A, Fostira, F, Foulkes, W D, Friebel, T M, Friedman, E, Frost, D, Gabrielson, M, Gammon, M D, Ganz, P A, Gapstur, S M, Garber, J, Gaudet, M, Gayther, S A, Gerdes, A-M, Ghoussaini, M, Giles, G, Glendon, G, Godwin, A K, Goldberg, M S, Goldgar, D E, González-Neira, A, Greene, M H, Gronwald, J, Guénel, P, Gunter, M J, Haeberle, L, Haiman, C A, Hamann, U, Hansen, T V O, Hart, S, Healey, S, Heikkinen, T, Henderson, B E, Herzog, J, Hogervorst, F B L, Hollestelle, A, Hooning, M J, Hoover, R N, Hopper, J L, Humphreys, K, Hunter, D J, Huzarski, T, Imyanitov, E N, Isaacs, C, Jakubowska, A, James, P A, Janavicius, R, Jensen, U B, John, E M, Jones, M, Kabisch, M, Kar, S, Karlan, B Y, Khan, S, Khaw, K-T, Kibriya, M G, Knight, J A, Ko, Y-D, Konstantopoulou, I, Kosma, V-M, Kristensen, V, Kwong, A, Laitman, Y, Lambrechts, D, Lázaro, C, Lee, E, Le Marchand, L, Lester, J, Lindblom, A, Lindor, N, Lindstrom, S, Liu, J, Long, J, Lubinski, J, Mai, P L, Makalic, E, Malone, K E, Mannermaa, A, Manoukian, S, Margolin, S, Marme, F, Martens, J W M, McGuffog, L, Meindl, A, Miller, A, Milne, R L, Miron, P, Montagna, M, Mazoyer, S, Mulligan, A M, Muranen, T A, Nathanson, K L, Neuhausen, S L, Nevanlinna, H, Nordestgaard, B G, Nussbaum, R L, Offit, K, Olah, E, Olopade, O I, Olson, J E, Osorio, A, Park, S K, Peeters, P H M, Peissel, B, Peterlongo, P, Peto, J, Phelan, C M, Pilarski, R, Poppe, B, Pylkäs, K, Radice, P, Rahman, N, Rantala, J, Rappaport, C, Rennert, G, Richardson, A, Robson, M, Romieu, I, Rudolph, A, Rutgers, E J, Sánchez, M-J, Santella, R M, Sawyer, E J, Schmidt, D F, Schmidt, M K, Schmutzler, R K, Schumacher, F, Scott, R J, Senter, L, Sharma, P, Simard, J, Singer, C F, Sinilnikova, O M, Soucy, P, Southey, M, Steinemann, D, Stenmark Askmalm, M, Stoppa-Lyonnet, D, Swerdlow, A, Szabo, C I, Tamimi, R, Tapper, W, Teixeira, M R, Teo, S-H, Terry, M B, Thomassen, M, Thompson, D J, Tihomirova, L, Toland, A E, Tollenaar, R A E M, Tomlinson, I, Truong, T, Tsimiklis, H, Teulé, A, Tumino, R, Tung, N, Turnbull, C, Ursin, G, van Deurzen, C H M, van Rensburg, E J, Varon-Mateeva, R, Wang, Z, Wang-Gohrke, S, Weiderpass, E, Weitzel, J N, Whittemore, A S, Wildiers, H, Winqvist, R, Yang, X R, Yannoukakos, D, Yao, S, Zamora, M P, Zheng, W, Hall, P, Kraft, P, Vachon, C, Slager, S, Chenevix-Trench, G, Pharoah, P D P, Monteiro, A N A, Garcia-Closas, M, Easton, D F & Antoniou, A C 2016, ' Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer ', Nature Communications, vol. 7, 11375 . https://doi.org/10.1038/ncomms11375
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Nature Communications, 7
Tomlinson, I 2016, ' Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer ', Nature Communications, vol. 7, 11375 . https://doi.org/10.1038/ncomms11375
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications [E], 7. Nature Publishing Group
Couch, F J, Kuchenbaecker, K B, Michailidou, K, Mendoza-Fandino, G A, Nord, S, Lilyquist, J, Olswold, C, Hallberg, E, Agata, S, Ahsan, H, Aittomäki, K, Ambrosone, C, Andrulis, I L, Anton-Culver, H, Arndt, V, Arun, B K, Arver, B, Barile, M, Barkardottir, R B, Barrowdale, D, Beckmann, L, Beckmann, M W, Benitez, J, Blank, S V, Blomqvist, C, Bogdanova, N V, Bojesen, S E, Bolla, M K, Bonanni, B, Brauch, H, Brenner, H, Burwinkel, B, Buys, S S, Caldes, T, Caligo, M A, Canzian, F, Carpenter, J, Chang-Claude, J, Chanock, S J, Chung, W K, Claes, K B M, Cox, A, Cross, S S, Cunningham, J M, Czene, K, Daly, M B, Damiola, F, Darabi, H, de la Hoya, M, Devilee, P, Diez, O, Ding, Y C, Dolcetti, R, Domchek, S M, Dorfling, C M, Dos-Santos-Silva, I, Dumont, M, Dunning, A M, Eccles, D M, Ehrencrona, H, Ekici, A B, Eliassen, H, Ellis, S, Fasching, P A, Figueroa, J, Flesch-Janys, D, Försti, A, Fostira, F, Foulkes, W D, Friebel, T, Friedman, E, Frost, D, Gabrielson, M, Gammon, M D, Ganz, P A, Gapstur, S M, Garber, J, Gaudet, M M, Gayther, S A, Gerdes, A-M, Ghoussaini, M, Giles, G G, Glendon, G, Godwin, A K, Goldberg, M S, Goldgar, D E, González-Neira, A, Greene, M H, Gronwald, J, Guénel, P, Gunter, M, Haeberle, L, Haiman, C A, Hamann, U, Hansen, T V O, Hart, S, Healey, S, Heikkinen, T, Henderson, B E, Herzog, J, Hogervorst, F B L, Hollestelle, A, Hooning, M J, Hoover, R N, Hopper, J L, Humphreys, K, Hunter, D J, Huzarski, T, Imyanitov, E N, Isaacs, C, Jakubowska, A, James, P, Janavicius, R, Jensen, U B, John, E M, Jones, M, Kabisch, M, Kar, S, Karlan, B Y, Khan, S, Khaw, K-T, Kibriya, M G, Knight, J A, Ko, Y-D, Konstantopoulou, I, Kosma, V-M, Kristensen, V, Kwong, A, Laitman, Y, Lambrechts, D, Lazaro, C, Lee, E, Le Marchand, L, Lester, J, Lindblom, A, Lindor, N, Lindstrom, S, Liu, J, Long, J, Lubinski, J, Mai, P L, Makalic, E, Malone, K E, Mannermaa, A, Manoukian, S, Margolin, S, Marme, F, Martens, J W M, McGuffog, L, Meindl, A, Miller, A, Milne, R L, Miron, P, Montagna, M, Mazoyer, S, Mulligan, A M, Muranen, T A, Nathanson, K L, Neuhausen, S L, Nevanlinna, H, Nordestgaard, B G, Nussbaum, R L, Offit, K, Olah, E, Olopade, O I, Olson, J E, Osorio, A, Park, S K, Peeters, P H, Peissel, B, Peterlongo, P, Peto, J, Phelan, C M, Pilarski, R, Poppe, B, Pylkäs, K, Radice, P, Rahman, N, Rantala, J, Rappaport, C, Rennert, G, Richardson, A, Robson, M, Romieu, I, Rudolph, A, Rutgers, E J, Sanchez, M-J, Santella, R M, Sawyer, E J, Schmidt, D F, Schmidt, M K, Schmutzler, R K, Schumacher, F, Scott, R, Senter, L, Sharma, P, Simard, J, Singer, C F, Sinilnikova, O M, Soucy, P, Southey, M, Steinemann, D, Stenmark-Askmalm, M, Stoppa-Lyonnet, D, Swerdlow, A, Szabo, C I, Tamimi, R, Tapper, W, Teixeira, M R, Teo, S-H, Terry, M B, Thomassen, M, Thompson, D, Tihomirova, L, Toland, A E, Tollenaar, R A E M, Tomlinson, I, Truong, T, Tsimiklis, H, Teulé, A, Tumino, R, Tung, N, Turnbull, C, Ursin, G, van Deurzen, C H M, van Rensburg, E J, Varon-Mateeva, R, Wang, Z, Wang-Gohrke, S, Weiderpass, E, Weitzel, J N, Whittemore, A, Wildiers, H, Winqvist, R, Yang, X R, Yannoukakos, D, Yao, S, Zamora, M P, Zheng, W, Hall, P, Kraft, P, Vachon, C, Slager, S, Chenevix-Trench, G, Pharoah, P D P, Monteiro, A A N, García-Closas, M, Easton, D F & Antoniou, A C 2016, ' Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer ', Nature Communications, vol. 7, 11375 . https://doi.org/10.1038/ncomms11375
Nature Communications, 7:11375. Nature Publishing Group
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Nature Publishing, 2018.

2018

0301 basic medicine, Oncology, General Physics and Astronomy, Genome-wide association study, Cyclophilins, Breast cancer, 3123 Gynaecology and paediatrics, Risk Factors, Brjóstakrabbamein, Genotype, BRCA2 MUTATION CARRIERS, Medicine and Health Sciences, CONFER SUSCEPTIBILITY, skin and connective tissue diseases, Cancer, GENE-EXPRESSION, Genetics, RISK, tRNA Methyltransferases, Multidisciplinary, Genome, VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801, Loci, BRCA1 Protein, Chromosome Mapping, COMMON VARIANTS, IDENTIFY, PANCREATIC-CANCER, 3. Good health, Multidisciplinary Sciences, Biological sciences, Receptors, Estrogen, Chromosomes, Human, Pair 2, Science & Technology - Other Topics, Female, NAF12, medicine.medical_specialty, Heterozygote, Science, 3122 Cancers, Locus (genetics), Breast Neoplasms, Biology, Breast Neoplasms/genetics, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Article, Càncer de mama, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Internal medicine, Pancreatic cancer, MD Multidisciplinary, medicine, Genetic predisposition, Journal Article, Humans, Genetic Predisposition to Disease, GENOME-WIDE ASSOCIATION, METAANALYSIS, Cancer och onkologi, Science & Technology, VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762, General Chemistry, Arfgengi, medicine.disease, TRNA Methyltransferases, VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762, 030104 developmental biology, Cancer and Oncology, Expression quantitative trait loci, Mutation, TELOMERE LENGTH, 3111 Biomedicine, Gene expression, VDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801, Genome-Wide Association Study

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