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1

Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,3',5-triiodo-l-thyronine (T3) highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae
Thomas H. Hutchinson ; Aoife Parsons ; Shinichi Miyagawa ; et al.
Aquatic toxicology (Amsterdam, Netherlands). 225

endocrine system Pituitary gland medicine.medical_special... Thyroid Hormones animal structures Corticotropin-Releasing... …
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2

Characterisation and expression of β1-, β2- and β3-adrenergic receptors in the fathead minnow (Pimephales promelas)
John P. Sumpter ; Mariann Rand-Weaver ; Thomas H. Hutchinson ; et al.
General and Comparative Endocrinology. 173:483-490

medicine.medical_special... DNA, Complementary Adrenergic receptor Amino Acid Motifs Cyprinidae Biology …
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3

Monoclonal antibody enzyme-linked immunosorbent assay to quantify vitellogenin for studies on environmental estrogens in the rainbow trout (Oncorhynchus mykiss)
Robert Blackwell ; Ronny van Aerle ; S. Maddix ; et al.
Environmental Toxicology and Chemistry. 21:47-54

endocrine system medicine.medical_special... animal structures biology medicine.drug_class animal diseases …
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4

Validation of the use of zebrafish larvae in visual safety assessment
William S. Redfern ; J.-P. Valentin ; Thomas H. Hutchinson ; et al.
Journal of Pharmacological and Toxicological Methods. 58:50-58

Pathology medicine.medical_special... Time Factors Drug-Related Side Effect... Drug Evaluation, Preclin... Pharmacology …
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5

Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow (Pimephales promelas)
Karen L. Thorpe ; Thomas H. Hutchinson ; Charles R. Tyler ; et al.
Aquatic Toxicology. 85:176-183

Male Agonist medicine.medical_special... Sex Differentiation Time Factors Estrone …
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6

Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances
Christina M. Lye ; Melanie Zerulla ; Grace H. Panter ; et al.
Environmental Toxicology and Chemistry. 21:319-326

medicine.medical_special... biology Health, Toxicology and M... Methoxychlor Juvenile fish Minnow …
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7

Effects of the synthetic estrogen 17α-ethinylestradiol on the life-cycle of the fathead minnow (Pimephales promelas)
Fred Siegmund ; Thomas H. Hutchinson ; Grace H. Panter ; et al.
Environmental Toxicology and Chemistry. 20:1216-1227

medicine.medical_special... animal structures Secondary sex characteri... Health, Toxicology and M... media_common.quotation_s... Biology …
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8

Relative Potencies and Combination Effects of Steroidal Estrogens in Fish
Karen L. Thorpe ; Rob I. Cummings ; John P. Sumpter ; et al.
Environmental Science & Technology. 37:1142-1149

medicine.medical_special... Estrone medicine.drug_class medicine.medical_treatme... Ethinyl Estradiol Steroid …
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9

[Untitled]
Ronny van Aerle ; Sue Maddix ; Charles R. Tyler ; et al.
Ecotoxicology. 11:423-434

endocrine system medicine.medical_special... Sexual differentiation Gonad Health, Toxicology and M... General Medicine …
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10

Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using theDrosophila melanogasterBIIcell in vitro assay
Thomas H. Hutchinson ; Laurence Dinan ; Tarlochan S. Dhadialla ; et al.
Environmental Toxicology and Chemistry. 20:2038-2046

Agonist medicine.medical_special... Ecdysteroid Receptor complex medicine.drug_class Health, Toxicology and M... …
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11

Assessing the Biological Potency of Binary Mixtures of Environmental Estrogens using Vitellogenin Induction in Juvenile Rainbow Trout (Oncorhynchus mykiss)
Karen L. Thorpe ; Charles R. Tyler ; Thomas H. Hutchinson ; et al.
Environmental Science & Technology. 35:2476-2481

Insecticides medicine.medical_special... Vitellogenins chemistry.chemical_compo... Vitellogenin Phenols …
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12

Development of an in vivo screening assay for estrogenic chemicals using juvenile rainbow trout (Oncorhynchus mykiss)
Malcolm J. Hetheridge ; Charles R. Tyler ; John P. Sumpter ; et al.
Environmental Toxicology and Chemistry. 19:2812-2820

endocrine system medicine.medical_special... biology Health, Toxicology and M... Methoxychlor Juvenile fish …
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13

An in vivo testing system for endocrine disruptors in fish early life stages using induction of vitellogenin
Heleanne Trip ; Ronny van Aerle ; Thomas H. Hutchinson ; et al.
Environmental Toxicology and Chemistry. 18:337-347

medicine.medical_special... food.ingredient biology Health, Toxicology and M... Minnow biology.organism_classif... …
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14

In vivo and in vitro liver and gill EROD activity in rainbow trout (Oncorhynchus mykiss) exposed to the beta-blocker propranolol
John P. Sumpter ; Duane B. Huggett ; Jon F. Ericson ; et al.
Environmental toxicology. 27(10)

Gill Gills endocrine system medicine.medical_special... animal structures medicine.drug_class …
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15

Seasonal trends in serum lysozyme activity and total protein concentration in dab (Limanda limandaL.) sampled from Lyme Bay, U.K
Thomas H. Hutchinson ; Margaret J. Manning
Fish & Shellfish Immunology. 6:473-482

medicine.medical_special... biology General Medicine Aquatic Science biology.organism_classif... LYME …
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16

Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow (Pimephales promelas) vitellogenin
Hans Kleivdal ; Kevin J. Kroll ; Grace H. Panter ; et al.
Aquatic toxicology (Amsterdam, Netherlands). 78(2)

medicine.medical_special... Time Factors Health, Toxicology and M... Population Cyprinidae Enzyme-Linked Immunosorb... …
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17

Development of chronic tests for endocrine active chemicals. Part 2. An extended fish early-life stage test for androgenic active chemicals in the fathead minnow (Pimephales promelas)
R.D. Stanley ; A. Hargreaves ; J. Bamforth ; et al.
Bogers, R, de Vries-Buitenweg, S, Gils, M, Baltussen, E, Hargreaves, A, van de Waart, B, de Roode, D, Legler, J & Murk, A J 2006, ' Development of chronic tests for endocrine active chemicals. Part 2. An extended fish early-life stage test for androgenic active chemicals in the fathead minnow (Pimephales promelas) ', Aquatic Toxicology, vol. 80, pp. 119-130 . https://doi.org/10.1016/j.aquatox.2006.07.020
Aquatic Toxicology 80 (2006) 2
Aquatic Toxicology, 80, 119-130. Elsevier
Aquatic Toxicology, 80(2), 119-130

Male Embryo, Nonmammalian Time Factors Secondary sex characteri... Health, Toxicology and M... Toxicology …
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18

Derivation of an aquatic predicted no-effect concentration for the synthetic hormone, 17 alpha-ethinyl estradiol
Thomas H. Hutchinson ; Colin R. Janssen ; Reinhard Länge ; et al.
Environmental sciencetechnology. 42(19)

medicine.medical_special... medicine.drug_class medicine.medical_treatme... Population Dynamics Biology Environment …
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19

Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow (Pimephales promelas)
Thomas Steger-Hartmann ; Thomas H. Hutchinson ; Daniel R. Dietrich ; et al.
Toxicology letters. 131(1-2)

Male medicine.medical_special... Sex Differentiation medicine.drug_class Cyprinidae Disorders of Sex Develop... …
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20

Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development
K.S. Hurd ; Charles R. Tyler ; R.D. Stanley ; et al.
Aquatic toxicology (Amsterdam, Netherlands). 70(1)

Male medicine.medical_special... medicine.drug_class Health, Toxicology and M... Cyprinidae Aquatic Science …
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