• Contemporary status of insecti...

*Result*: Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans

Title:
Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans
Authors:
Moyes, Catherine, Vontas, John, Martins, Ademir, J, Ng, Lee, Ching, Koou, Sin, Ying, Dusfour, Isabelle, Raghavendra, Kamaraju, Pinto, João, Corbel, Vincent, David, Jean-Philippe, Weetman, David
Contributors:
Big Data Institute, University of Oxford, Institute of Molecular Biology and Biotechnology (IMBB-FORTH), Foundation for Research and Technology - Hellas (FORTH), Agricultural University of Athens, Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ), Pasteur Network (Réseau International des Instituts Pasteur), Environment Health Institute Singapore, National Environment Agency Singapore (NEA), Entomologie médicale Cayenne, Guyane française, Institut Pasteur de la Guyane, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur), National Institute of Malaria Research New Dehli, Inde (NIMR), Indian Council of Medical Research New Dehli (ICMR), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD Occitanie ), Laboratoire d'Ecologie Alpine (LECA), Université Savoie Mont Blanc (USMB Université de Savoie Université de Chambéry )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes 2016-2019 (UGA 2016-2019 ), Liverpool School of Tropical Medicine (LSTM), The preparation of this review was funded by an award from the World Health Organization's Special Programme for Research and Training in Tropical Diseases (http://www.who.int/tdr/) to VC, JPD, and the WIN network. The bioassay data extraction was funded by Wellcome Trust (https://wellcome.ac.uk/) grant 108440/Z/15/Z awarded to CLM., We thank Hilary Ranson for providing the complete datasets from her 2010 review. We also thank Maria de Lourdes Macoris, Laboratório de Entomologia Aplicada, Sucen, São Paulo, for compiling an extensive dataset for Brazil, and Poonam Sharma Velamuri and Elamathi Natarajan for their work on the data for India. We thank the following groups and individuals for contributing unpublished datasets: Gonçalo Seixas and Carla Alexandra Sousa, Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Beniamino Caputo and Alessandra della Torre, Istituto Pasteur-Fondazione Cenci-Bolognetti, Dipartimento di Sanità Pubblica e Malattie Infettive, Università “Sapienza”, Rome, Italy, Sébastien Marcombe and Paul Brey, Institut Pasteur du Laos, Vientiane, Lao People’s Democratic Republic Waraporn Juntarajumnong, Kasetsart University, Bangkok, Thailand, Ferdinand V. Salazar, Department of Medical Entomology, Research Institute of Tropical Medicine, Department of Health, Philippines, Laboratório de Entomologia Aplicada (LEnA), Sucen, Marília, SP/ Brazil.
Source:
ISSN: 1935-2727.
Publisher Information:
CCSD
Public Library of Science
Publication Year:
2017
Collection:
Université de Montpellier: HAL
Subject Terms:
MESH: Aedes/drug effects, MESH: Aedes/genetics, MESH: Humans, MESH: Inactivation, Metabolic, MESH: Insect Control/methods, MESH: Insect Vectors/drug effects, MESH: Insect Vectors/genetics, MESH: Insect Vectors/virology, MESH: Insecticide Resistance/genetics, MESH: Insecticides/classification, MESH: Insecticides/pharmacology, MESH: Larva/drug effects, MESH: Aedes/virology, MESH: Africa, MESH: Americas, MESH: Animals, MESH: Arboviruses/classification, MESH: Arboviruses/pathogenicity, MESH: Asia, MESH: Biological Assay, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology
Document Type:
*Academic Journal* article in journal/newspaper
Language:
English
Relation:
info:eu-repo/semantics/altIdentifier/pmid/28727779; PUBMED: 28727779; PUBMEDCENTRAL: PMC5518996
DOI:
10.1371/journal.pntd.0005625
Availability:
https://hal.umontpellier.fr/hal-02013555
https://hal.umontpellier.fr/hal-02013555v1/document
https://hal.umontpellier.fr/hal-02013555v1/file/journal.pntd.0005625.pdf
https://doi.org/10.1371/journal.pntd.0005625
Rights:
http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
Accession Number:
edsbas.12CAB082
Database:
BASE

*Further Information*

*International audience ; Both Aedes aegytpi and Ae. albopictus are major vectors of 5 important arboviruses (namely chikungunya virus, dengue virus, Rift Valley fever virus, yellow fever virus, and Zika virus), making these mosquitoes an important factor in the worldwide burden of infectious disease. Vector control using insecticides coupled with larval source reduction is critical to control the transmission of these viruses to humans but is threatened by the emergence of insecticide resistance. Here, we review the available evidence for the geographical distribution of insecticide resistance in these 2 major vectors worldwide and map the data collated for the 4 main classes of neurotoxic insecticide (carbamates, organochlorines, organophosphates, and pyrethroids). Emerging resistance to all 4 of these insecticide classes has been detected in the Americas, Africa, and Asia. Target-site mutations and increased insecticide detoxification have both been linked to resistance in Ae. aegypti and Ae. albopictus but more work is required to further elucidate metabolic mechanisms and develop robust diagnostic assays. Geographical distributions are provided for the mechanisms that have been shown to be important to date. Estimating insecticide resistance in unsampled locations is hampered by a lack of standardisation in the diagnostic tools used and by a lack of data in a number of regions for both resistance phenotypes and genotypes. The need for increased sampling using standard methods is critical to tackle the issue of emerging insecticide resistance threatening human health. Specifically, diagnostic doses and well-characterised susceptible strains are needed for the full range of insecticides used to control Ae. aegypti and Ae. albopictus to standardise measurement of the resistant phenotype, and calibrated diagnostic assays are needed for the major mechanisms of resistance.*