*Result*: Emotion recognition deficits in temporal lobe epilepsy are non-lateralized and independent of surgery.

Title:
Emotion recognition deficits in temporal lobe epilepsy are non-lateralized and independent of surgery.
Authors:
Amlerova J; Motol Epilepsy Centre, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. Electronic address: jana.amler@gmail.com., Pytelova V; Motol Epilepsy Centre, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Angelucci F; Memory Clinic, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic; International Clinical Research Centre, St. Anne's University Hospital Brno, Brno, Czech Republic., Andel R; Memory Clinic, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic; International Clinical Research Centre, St. Anne's University Hospital Brno, Brno, Czech Republic; Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, USA., Hort J; Memory Clinic, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic; International Clinical Research Centre, St. Anne's University Hospital Brno, Brno, Czech Republic., Javurkova A; Department of Psychology, Motol University Hospital, Prague, Czech Republic., Marusic P; Motol Epilepsy Centre, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Source:
Epilepsy & behavior : E&B [Epilepsy Behav] 2026 Mar; Vol. 176, pp. 110906. Date of Electronic Publication: 2026 Jan 22.
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: Academic Press Country of Publication: United States NLM ID: 100892858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-5069 (Electronic) Linking ISSN: 15255050 NLM ISO Abbreviation: Epilepsy Behav Subsets: MEDLINE
Imprint Name(s):
Original Publication: San Diego, CA : Academic Press, c2000-
Contributed Indexing:
Keywords: Emotion recognition; Epilepsy; Epilepsy surgery; Temporal lobe
Entry Date(s):
Date Created: 20260123 Date Completed: 20260214 Latest Revision: 20260214
Update Code:
20260215
DOI:
10.1016/j.yebeh.2026.110906
PMID:
41576838
Database:
MEDLINE

*Further Information*

*To examine whether patients with unilateral temporal lobe epilepsy (TLE) show deficits in recognizing emotions from facial expressions and vocal prosody, and whether these impairments differ by seizure focus or surgical status.
Methods: Thirty-four patients with TLE were evaluated before or after temporal lobe resection for drug-resistant epilepsy. Thirty right-handed healthy controls without neurological or psychiatric history were included. Emotion recognition was assessed using the Emotion Recognition Test (ERT), consisting of a Facial ERT (adapted from Ekman and Friesen's facial expression set) and a Prosody ERT developed in collaboration with professional actors using two neutral Czech sentences. Both subtests included five emotions: anger, disgust, fear, happiness, and sadness.
Results: TLE patients showed a general impairment in emotion recognition across both modalities. Total prosody and facial emotion scores were significantly lower than in controls. Prosody deficits and facial emotion scores were independent of age, disease duration, and education. No significant differences were found between right and left TLE, or between pre- and postoperative groups.
Significance: Deficits in emotion recognition from face and voice in patients with TLE were not lateralized and did not differ between pre- and postoperative TLE groups. This may indicate persistent socio-emotional processing abnormalities that may contribute to the social and behavioral difficulties observed in TLE people. Longitudinal studies are needed in this field.
(Copyright © 2026 The Authors. Published by Elsevier Inc. All rights reserved.)*

*Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.*