*Result*: Insect-derived Compounds as Novel Source for Drug Discovery: A Systematic Review and Critical In Silico Analysis.

Insect-derived Compounds as Novel Source for Drug Discovery: A Systematic Review and Critical In Silico Analysis.

Adipo M; International Centre of Insect Physiology and Ecology, Nairobi, Kenya.; Department of Physical Sciences, University of Embu, Embu, Kenya., Mudalungu CM; International Centre of Insect Physiology and Ecology, Nairobi, Kenya.; Department of Chemistry and Material Science, The Technical University of Kenya (TUK), Nairobi, Kenya., Santos CBR; Graduate Program in Biotechnology and Biodiversity-Network BIONORTE, Federal University of Amapá, Macapá, Brazil.; Laboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, Macapá, Brazil., Kimani NM; Department of Physical Sciences, University of Embu, Embu, Kenya., Tanga CM; International Centre of Insect Physiology and Ecology, Nairobi, Kenya.

Chemistry & biodiversity [Chem Biodivers] 2026 Feb; Vol. 23 (2), pp. e02495. Date of Electronic Publication: 2025 Dec 12.

Journal Article; Systematic Review; Review

English

Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

Original Publication: Zürich, Switzerland : Hoboken, NJ : Verlag Helvetica Chimica Acta ; Distributed in the USA by Wiley, c2004-

Insecta*/chemistry , Insecta*/metabolism , Biological Products*/chemistry , Biological Products*/pharmacology , Biological Products*/isolation & purification , Drug Discovery*, Animals ; Humans ; Computer Simulation

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LS/2020/154 Australian Centre for International Agricultural Research (ACIAR); 2021 FOD 030 Rockefeller Foundation; 101060762 Horizon Europe; 101136739 Horizon Europe; Curt Bergfors Foundation Food Planet Prize Award; RAF-3058 KEN-18/0005 Section for research, innovation, and higher education; Swedish International Development Cooperation Agency (SIDA); Swiss Agency for Development and Cooperation (SDC); Norwegian Agency for Development Cooperation (NORAD); German Federal Ministry for Economic Cooperation and Development (BMZ)

Keywords: ADMET properties; FDA; drug‐likeness; insects; microbiota; natural products; pharmacokinetics

0 (Biological Products)

Date Created: 20251212 Date Completed: 20260131 Latest Revision: 20260131

20260201

10.1002/cbdv.202502495

41387353

MEDLINE