• Recent insights in the de...

*Result*: Recent insights in the development and functions of insect hemocytes.

Title:
Recent insights in the development and functions of insect hemocytes.
Authors:
Strand MR; Department of Entomology, University of Georgia, Athens, GA, USA. Electronic address: mrstrand@uga.edu.
Source:
Current opinion in insect science [Curr Opin Insect Sci] 2026 Feb; Vol. 73, pp. 101434. Date of Electronic Publication: 2025 Sep 15.
Publication Type:
Journal Article; Review
Language:
English
Journal Info:
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101635599 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2214-5753 (Electronic) NLM ISO Abbreviation: Curr Opin Insect Sci Subsets: MEDLINE
Imprint Name(s):
Original Publication: Amsterdam : Elsevier
MeSH Terms:
Hemocytes*/physiology , Hemocytes*/immunology , Insecta*/growth & development , Insecta*/immunology, Animals ; Signal Transduction ; Cell Differentiation
Entry Date(s):
Date Created: 20250917 Date Completed: 20251211 Latest Revision: 20251211
Update Code:
20260130
DOI:
10.1016/j.cois.2025.101434
PMID:
40962030
Database:
MEDLINE

*Further Information*

*Hemocytes mediate defense responses that are collectively referred to as cellular immunity. Here, I highlight recent progress in the study of hemocyte ontogeny and function. Studies conducted primarily in D. melanogaster, mosquitoes, and Lepidoptera identify a number of transcription factors and signaling pathways that regulate hemocyte differentiation and proliferation. Single-cell RNA sequencing studies identify genes that distinguish transitional states in different hemocyte populations and changes that occur during immune responses. Several new studies expand the understanding of the functions of sessile hemocytes. Recent results also enhance understanding of the signaling pathways that regulate hemocyte functions.
(Copyright © 2025 Elsevier Inc. All rights reserved.)*

*Declaration of Competing Interest The author declares he has no known competing financial interests or personal relationships that could inappropriately influence work reported in this paper.*