• The Proteins API: accessing ke...

*Result*: The Proteins API: accessing key integrated protein and genome information.

Title:
The Proteins API: accessing key integrated protein and genome information.
Authors:
Nightingale A; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Antunes R; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Alpi E; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Bursteinas B; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Gonzales L; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Liu W; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Luo J; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Qi G; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Turner E; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK., Martin M; EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
Source:
Nucleic acids research [Nucleic Acids Res] 2017 Jul 03; Vol. 45 (W1), pp. W539-W544.
Publication Type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Language:
English
Journal Info:
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Imprint Name(s):
Publication: 1992- : Oxford : Oxford University Press
Original Publication: London, Information Retrieval ltd.
MeSH Terms:
Genome, Human* , Internet* , User-Computer Interface*, Copper-Transporting ATPases/*genetics , Hepatolenticular Degeneration/*genetics, Biomarkers/metabolism ; Copper-Transporting ATPases/metabolism ; Hepatolenticular Degeneration/metabolism ; Hepatolenticular Degeneration/pathology ; Proteomics/methods ; Animals ; Databases, Genetic ; Gene Expression ; Humans ; Mice ; Molecular Sequence Annotation
References:
Nucleic Acids Res. 2015 Jan;43(Database issue):D805-11. (PMID: 25355519)
J Med Genet. 2007 Nov;44(11):673-88. (PMID: 17717039)
Nature. 2015 Oct 1;526(7571):68-74. (PMID: 26432245)
Bioinformatics. 2017 Mar 7;:null. (PMID: 28334231)
Mol Cell Proteomics. 2012 Mar;11(3):M111.014068. (PMID: 22301388)
Science. 2015 Jan 23;347(6220):1260419. (PMID: 25613900)
Nucleic Acids Res. 2017 Jan 4;45(D1):D158-D169. (PMID: 27899622)
Mol Cell Proteomics. 2013 Mar;12 (3):638-50. (PMID: 23242552)
Nucleic Acids Res. 2013 Jan;41(Database issue):D1063-9. (PMID: 23203882)
Bioinformatics. 2013 Apr 15;29(8):1103-4. (PMID: 23435069)
J Proteome Res. 2013 Jan 4;12(1):162-71. (PMID: 23215161)
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D655-8. (PMID: 16381952)
Nature. 2016 Aug 17;536(7616):285-91. (PMID: 27535533)
Nucleic Acids Res. 2016 Jan 4;44(D1):D862-8. (PMID: 26582918)
PLoS Biol. 2011 Jul;9(7):e1001091. (PMID: 21750661)
Database (Oxford). 2017 Jan 1;2017(1):null. (PMID: 28365736)
Grant Information:
U41 HG007822 United States HG NHGRI NIH HHS
Substance Nomenclature:
0 (Biomarkers)
EC 7.2.2.8 (ATP7B protein, human)
EC 7.2.2.8 (Copper-Transporting ATPases)
Entry Date(s):
Date Created: 20170407 Date Completed: 20190619 Latest Revision: 20210103
Update Code:
20260130
PubMed Central ID:
PMC5570157
DOI:
10.1093/nar/gkx237
PMID:
28383659
Database:
MEDLINE

*Further Information*

*The Proteins API provides searching and programmatic access to protein and associated genomics data such as curated protein sequence positional annotations from UniProtKB, as well as mapped variation and proteomics data from large scale data sources (LSS). Using the coordinates service, researchers are able to retrieve the genomic sequence coordinates for proteins in UniProtKB. This, the LSS genomics and proteomics data for UniProt proteins is programmatically only available through this service. A Swagger UI has been implemented to provide documentation, an interface for users, with little or no programming experience, to 'talk' to the services to quickly and easily formulate queries with the services and obtain dynamically generated source code for popular programming languages, such as Java, Perl, Python and Ruby. Search results are returned as standard JSON, XML or GFF data objects. The Proteins API is a scalable, reliable, fast, easy to use RESTful services that provides a broad protein information resource for users to ask questions based upon their field of expertise and allowing them to gain an integrated overview of protein annotations available to aid their knowledge gain on proteins in biological processes. The Proteins API is available at (http://www.ebi.ac.uk/proteins/api/doc).
(© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.)*